Wednesday, August 8, 2012

Carisoprodol in clinial trials for back pain | Recreation and Sports

August 7th, 2012 by Leave a reply ?

As millions of people around the world can testify, back pain can come out of nowhere and force people to stop whatever they are doing and lie down. When doctors can be persuaded to identify causes, they point vaguely to stressing muscles and joints when lifting heavy weights, or twisting during a fall. When we explain we have not recently attempted anything strenuous nor fallen over, they resort to notions we have somehow overused our muscles and ligaments, or we have put pressure on the nerve roots because we don?t sit up straight, or that we?re just getting old. This does not make us feel any better, nor does it inspire much confidence as we ask what treatments are available.

The problem can be simply stated. Medical science does not know much about back pain, and relies on trial and error to find a treatment that will work on us. In many cases, we just get better. However, it?s become quite common for doctors to prescribe some kind of muscle relaxers. As justification, the doctors are able to point to a number of clinical trials in which these drugs have relieved stiffness and improved mobility. Indeed, some evidence suggests the drugs are directly effective in changing the way the muscles work.

This would be wonderful news if Carisoprodol was a safer drug. Unfortunately, this drug was developed and put on to the market before the FDA required the pharmaceutical industry to perform standard tests to prove drugs effective and safe. So even though there have been some clinical trials, they have been small scale and not scientifically useful. This leaves us with a problem. This is a powerful drug and it does relax muscles, mainly through its sedative effect. Because it?s long out of patent protection, it?s sold as a generic, i.e. it?s cheap. But unless it?s used very carefully, we can quickly become dependent on it and there are withdrawal symptoms when we try to stop. Use Carisoprodol in very short bursts only for maximum effect.

Source: http://www.ypsummit.org/178-carisoprodol-in-clinial-trials-for-back-pain.html

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